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Sitagliptin
Clinical data
Pronunciation/ s ɪ t ə ˈ ɡ l ɪ p t ɪ n / ( listen )
Trade namesJanuvia, Tesavel, Xelevia, others
AHFS/Drugs.comMonograph
MedlinePlusa606023
License dataEU  EMA:  by INN, US   FDA: Sitagliptin
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationBy mouth
ATC codeA10BH01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability87%
Protein binding38%
MetabolismLiver (CYP3A4- and CYP2C8-mediated)
Elimination half-life8 to 14 h [1]
ExcretionKidney (80%) [1]
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Sitagliptin instruction
Tablet name Sitagliptin
Sitagliptin alternative namessitagliptina, sitagliptine, sitagliptinum, tesavel, xelevia
Active substancejanuvia
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